Liver Diseases




Liver disease can manifest in many different ways. Characteristic manifestations include jaundice (a yellowish discoloration of the skin and whites of the eyes), cholestasis (reduction or stoppage of bile flow), liver enlargement, portal hypertension (abnormally high blood pressure in the veins that bring blood from the intestine to the liver), ascites (accumulation of fluid in the abdominal cavity), hepatic encephalopathy (deterioration of brain function due to buildup of toxic substances normally removed by the brain), and liver failure.

Sometimes the manifestations of liver disease are not obvious. For example, symptoms may include fatigue, a feeling of unwellness, loss of appetite, and mild weight loss. However, these symptoms are also typical of many other diseases. Thus, liver disease can easily be overlooked, particularly in its early stages.

Signs and symptoms of liver problems include:
  • Discolored skin and eyes that appear yellowish
  • Abdominal pain and swelling
  • Itchy skin that doesn't seem to go away
  • Dark urine color
  • Pale stool color
  • Bloody or tar-colored stool
  • Chronic fatigue
  • Nausea
  • Loss of appetite
To keep your liver healthy and avoid any potential liver problems, see your doctor if you have any signs or symptoms that concern you.

Prevent liver problems:

Here are the most important things you can do to protect your liver:
  • Drink alcohol in moderation, if at all. Over many years, more than one drink a day for women and more than two drinks a day for men may be enough to lead to cirrhosis. Use of certain drugs, including some illegal drugs, also can cause liver disease.
  • Don't mix other drugs with alcohol. Acetaminophen (Tylenol, others) can be toxic to the liver even if you drink in moderation.
  • Get vaccinated. If you're at increased risk of contracting hepatitis or if you've already been infected with any form of the hepatitis virus, talk to your doctor about getting the hepatitis B vaccine. A vaccine is also available for hepatitis A.
  • Use medications wisely. Only use prescription and nonprescription drugs when you need them and take only the recommended doses. Talk to your doctor before mixing herbal supplements or prescription or nonprescription drugs.
  • Beware of certain supplements. Herbal supplements that can be toxic to the liver include kava, comfrey, chaparral, kombucha tea, pennyroyal and skullcap. Also avoid high doses of vitamins A, D, E and K.
  • Avoid contact with other people's blood and body fluids. Hepatitis viruses can be spread by accidental needle sticks, improper cleanup of blood or body fluids, and sharing intravenous needles. It's also possible to become infected by sharing razor blades or toothbrushes or by having unsafe sex.
  • Be careful with aerosol sprays. When you use an aerosol cleaner, make sure the room is ventilated, or wear a mask. Take similar protective measures when spraying insecticides, fungicides, paint and other toxic chemicals.
  • Watch what gets on your skin. When using insecticides and other toxic chemicals, cover your skin with gloves, long sleeves, a hat and a mask.
  • Don't eat too many fatty foods. Your liver makes all the cholesterol your body needs. Eating a well-balanced, nourishing diet will help your liver do its job properly. A regular exercise program will help keep your liver healthy, too.
  • Watch your weight. Even if you don't drink alcohol, obesity can cause a condition called nonalcoholic fatty liver disease, which may include fatty liver, hepatitis and cirrhosis.
Credit: National Institute of Health.
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