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Cannabis




Cannabis sativa L., the cannabis plant, grows wild throughout most of the tropic and temperate regions of the world. Prior to the advent of synthetic fibers, the cannabis plant was cultivated for the tough fiber of its stem. In the United States, cannabis is legitimately grown only for scientific research.

Cannabis Products

Cannabis products are usually smoked. Their effects are felt within minutes, reach their peak in 10 to 30 minutes, and may linger for two or three hours. The effects experienced often depend upon the experience and expectations of the individual user, as well as the activity of the drug itself. Low doses tend to induce a sense of well-being and a dreamy state of relaxation, which may be accompanied by a more vivid sense of sight, smell, taste, and hearing, as well as by subtle alterations in thought formation and expression. This state of intoxication may not be noticeable to an observer. However, driving, occupational, or household accidents may result from a distortion of time and space relationships and impaired motor coordination. Stronger doses intensify reactions. The individual may experience shifting sensory imagery, rapidly fluctuating emotions, fragmentary thoughts with disturbing associations, an altered sense of self-identity, impaired memory, and a dulling of attention despite an illusion of heightened insight. High doses may result in image distortion, a loss of personal identity, fantasies, and hallucinations.

Three drugs that come from cannabis--marijuana, hashish, and hashish oil--are distributed on the U.S. illicit market. Having no currently accepted medical use in treatment in the United States, they remain under Schedule I of the CSA. Today, cannabis is illicitly cultivated, both indoors and out, to maximize its THC content, thereby producing the greatest possible psychoactive effect.

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Marijuana

Marijuana is a dry, shredded mix of flowers, stems, seeds and leaves of the hemp plant Cannabis sativa. People usually smoke it as a cigarette or in a pipe. It is the most commonly abused illegal drug in the United States.

Marijuana is the most frequently encountered illicit drug worldwide. In the United States, according to the 2003 Monitoring the Future Study, 57 percent of adults aged 19 to 28 reported having used marijuana in their lifetime. Among younger Americans, 17.5 percent of 8th graders and 46.1 percent of 12th graders had used marijuana in their lifetime. The term "marijuana," as commonly used, refers to the leaves and flowering tops of the cannabis plant that are dried to produce a tobacco-like substance. Marijuana varies significantly in its potency, depending on the source and selection of plant materials used.

Abusing marijuana can result in problems with memory, learning and social behavior. Longer term it can lead to problems such as lung cancer and increased risk of infections. It can interfere with family, school, work and other activities.

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Hashish

Hashish consists of the THC-rich resinous material of the cannabis plant, which is collected, dried, and then compressed into a variety of forms, such as balls, cakes, or cookie-like sheets. Pieces are then broken off, placed in pipes, and smoked. The Middle East, North Africa, and Pakistan/Afghanistan are the main sources of hashish. The THC content of hashish that reached the United States, where demand is limited, averaged about five percent in the 1990s.

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Hashish Oil

The term "hash oil" is used by illicit drug users and dealers, but is a misnomer in suggesting any resemblance to hashish. Hash oil is produced by extracting the cannabinoids from plant material with a solvent. The color and odor of the resulting extract will vary, depending on the type of solvent used. Current samples of hash oil, a viscous liquid ranging from amber to dark brown in color, average about 15 percent THC. In terms of its psychoactive effect, a drop or two of this liquid on a cigarette is equal to a single "joint" of marijuana.

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Health Consequences

Marijuana affects alertness, concentration, perception, coordination, and reaction time- skills that are necessary for safe driving. A roadside study of reckless drivers in Tennessee found that 33 percent of all subjects who were not under the influence of alcohol and who were tested for drugs at the scene of their arrest tested positive for marijuana. In a 2003 Canadian study, one in five students admitted to driving within an hour of using marijuana. Marijuana smoke contains 50 percent to 70 percent more carcinogenic hydrocarbons than does tobacco smoke.10 Using marijuana may promote cancer of the respiratory tract and disrupt the immune system.

Heavy marijuana use impairs the ability of young people to concentrate and retain information during their peak learning years. Tetrahydrocannabinol (THC), the main active chemical in marijuana, changes the way sensory information gets into and is processed by the part of the brain that is crucial for learning and memory. Marijuana users in their later teen years are more likely to have an increased risk of delinquency and more friends who exhibit deviant behavior. They also tend to have more sexual partners and are more likely to engage in unsafe sex.

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Treatment Approaches

Drug addiction is a complex but treatable brain disease. It is characterized by compulsive drug craving, seeking, and use that persist even in the face of severe adverse consequences. For many people, drug addiction becomes chronic, with relapses possible even after long periods of abstinence. In fact, relapse to drug abuse occurs at rates similar to those for other well-characterized, chronic medical illnesses such as diabetes, hypertension, and asthma. As a chronic, recurring illness, addiction may require repeated treatments to increase the intervals between relapses and diminish their intensity, until abstinence is achieved. Through treatment tailored to individual needs, people with drug addiction can recover and lead productive lives.

Medications can be used to help re-establish normal brain function and to prevent relapse and diminish cravings throughout the treatment process. Currently, we have medications for opioid (heroin, morphine) and tobacco (nicotine) addiction, and are developing others for treating stimulant (cocaine, methamphetamine) and cannabis (marijuana) addiction.

Behavioral Treatments help patients engage in the treatment process, modify their attitudes and behaviors related to drug abuse, and increase healthy life skills. Behavioral treatments can also enhance the effectiveness of medications and help people stay in treatment longer.

Residential treatment programs can also be very effective, especially for those with more severe problems. For example, therapeutic communities (TCs) are highly structured programs in which patients remain at a residence, typically for 6 to 12 months. Patients in TCs may include those with relatively long histories of drug addiction, involvement in serious criminal activities, and seriously impaired social functioning. TCs are now also being designed to accommodate the needs of women who are pregnant or have children. The focus of the TC is on the re-socialization of the patient to a drug-free, crime-free lifestyle.

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Information obtained from National Institute of Health
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